We aim to characterize viral promoters to control the production of proteins in insect cells with the goal of creating a manufacturing assembly line for complex biologics.
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Using humanized S. cerevisiae (baker's yeast) as a platform to develop new medicines.
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Metabolomics and computational analysis of cells in cultures, bioreactors and biological systems.
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I believe that Synthetic Biology will continue to play a significant role in medical innovation, including engineered virus and engineered immune cells that can cure cancer.
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We investigate how phenotypes and disease states emerge from the interplay of genetic determinants in yeast and human cells.
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Research in the Karas lab is focused on developing innovative genetic tools to enable the engineering of microbes to produce medicines, DNA storage technologies, food and next-generation fuels.
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Intersection of genome sequencing/bioinformatics, interpretation and editing.
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BioZone aims to use Bioengineering to create a sustainable world by making industrial processes more sustainable, remediating humanity's environmental impact, and improving health outcome.
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Our group primarily works on engineering metabolism in bacteria and yeast to produce chemicals and therapeutic molecules. Through the use of computational strategies on genome scale metabolic models of these organisms, we identify genetic intervention strategies to enhance target molecule production.
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Chimeric antigen receptor T cells (CAR-T) are an exciting new avenue to redirect immune cells to target and kill cancer. While breakthroughs in CAR-T therapy have led to life-saving treatments for patients with previously incurable leukemia, such therapies have been less successful against solid tumours.
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As a bioethicist, I am interested in the science and development of synthetic biology and in ethical questions that arise from its use, as well as in its impact on health care, the workforce and the environment.
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My laboratory is mainly interested in microbial systems and synthetic biology. We use and develop cutting-edge approaches to understand and engineer bacterial cells.
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Synthetic biology strategies for the biosynthesis of fine chemicals, especially lipid-based drugs and biofuels
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My research group at the University of Guelph is developing new CRISPR-based platforms for functional genomic analysis in fungal pathogens.
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We aim to engineer microalgae to produce proteins for medical and industrial uses as well as engineer metabolic pathways in microbial platforms for the production of isoprenoids.
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The principal theme of Prof. Yadav’s research is the utilization of metabolic & enzyme engineering to investigate and customize novel biosynthetic enzymes that can convert biomass-derived feedstocks into value-added chemicals.
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Research in the Zandstra Laboratory is focused on the generation of functional tissue from somatic and pluripotent stem cells. Our quantitative, technology-driven approach strives to gain new insights into fundamental mechanisms that control stem cell fate and to develop robust technologies for the propagation of stem cells and their derivatives.
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My lab will open in July 2018 at the Department of Molecular and Cellular Biology, University of Guelph. We are creating synthetic proteins using bimolecular engineering approaches to accelerate understanding of biology and development of novel therapeutics.
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