SynBio Canada

Academic Profiles

Academic Profiles

Dr. Radhakrishnan Mahadevan

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Professor, Associate Chair & Graduate Studies Coordinator, University of Toronto

Email Address: krishna.mahadevan@utoronto.ca

Bio: Our group primarily works on engineering metabolism in bacteria and yeast to produce chemicals and therapeutic molecules. Through the use of computational strategies on genome scale metabolic models of these organisms, we identify genetic intervention strategies to enhance target molecule production. Synthetic biological tools help us assemble and engineer pathways in microorganisms. We use synthetic gene regulatory circuits to dynamically control metabolism in host organisms. The ability to dynamically control metabolism based on environmental inputs finds application in a variety of different areas including therapeutics and industrial biotechnology.

Website: www.lmse.utoronto.ca

Twitter: @LMSE_UofT