We aim to characterize viral promoters to control the production of proteins in insect cells with the goal of creating a manufacturing assembly line for complex biologics.
Read MoreWe take advantage of latest synthetic biology approaches to increase the scale or resolution at which we can interrogate the systems biology of the cell.
Read MoreMetabolomics and computational analysis of cells in cultures, bioreactors and biological systems.
Read MoreI believe that Synthetic Biology will continue to play a significant role in medical innovation, including engineered virus and engineered immune cells that can cure cancer.
Read MoreWe investigate how phenotypes and disease states emerge from the interplay of genetic determinants in yeast and human cells.
Read MoreIntersection of genome sequencing/bioinformatics, interpretation and editing.
Read MoreChimeric antigen receptor T cells (CAR-T) are an exciting new avenue to redirect immune cells to target and kill cancer. While breakthroughs in CAR-T therapy have led to life-saving treatments for patients with previously incurable leukemia, such therapies have been less successful against solid tumours.
Read MoreWe develop new methods in the domains of Genomics and Synthetic Biology, using microfluidics and computational biology.
Read MoreResearch in the Zandstra Laboratory is focused on the generation of functional tissue from somatic and pluripotent stem cells. Our quantitative, technology-driven approach strives to gain new insights into fundamental mechanisms that control stem cell fate and to develop robust technologies for the propagation of stem cells and their derivatives.
Read MoreMy lab will open in July 2018 at the Department of Molecular and Cellular Biology, University of Guelph. We are creating synthetic proteins using bimolecular engineering approaches to accelerate understanding of biology and development of novel therapeutics.
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